A high content imaging assay for identification of specific inhibitors of native Plasmodium liver stage protein synthesis
James L. McLellan, Beatriz Morales-Hernandez, Sarah Saeger, Kirsten K. Hanson
The paper develops a high-content imaging assay to identify Plasmodium liver stage protein synthesis inhibitors and identifies two quinoline-4-carboxamides with distinct antiplasmodial and translation inhibition profiles.
Antimicrobial Agents and Chemotherapy · Sep 10, 2024Peer-reviewedMicrobiology