Author

James L. McLellan

The University of Texas at San AntonioORCID 0009-0007-6407-6572Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Kirsten K. HansoniD· 2 shared Beatriz Morales-Hernandez· 1 shared Sarah SaegeriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersMicrobiology

Kirsten K. HansonORCID

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2 papers

Recent·Most cited

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedSep 10, 2024

A high content imaging assay for identification of specific inhibitors of native Plasmodium liver stage protein synthesis

James L. McLellan, Beatriz Morales-Hernandez, Sarah Saeger, Kirsten K. Hanson

The paper develops a high-content imaging assay to identify Plasmodium liver stage protein synthesis inhibitors and identifies two quinoline-4-carboxamides with distinct antiplasmodial and translation inhibition profiles.

2 citations

mouseimaging

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MicrobiologyLife Science AlliancePeer-reviewedApr 4, 2024

Translation inhibition efficacy does not determine the Plasmodium berghei liver stage antiplasmodial efficacy of protein synthesis inhibitors

James L. McLellan, Kirsten K. Hanson

This study shows that the effectiveness of translation inhibitors against Plasmodium berghei liver stages is not determined by their translation inhibition efficacy, as DDD107498, a weak inhibitor, had strong antimalarial effects.

8 citations

mouseproteomics

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