CURE-ating the substrate scope and functional residues of nonheme iron(II) α-ketoglutarate dependent hydroxylase BesE
Austin R. Hopiavuori, Beau S. Andre, Emely D. Avalos, Surina L. Beal, George R. Beck, Charles J. Choi, Elizabeth M. Dolzhansky, Michelle X. Du, Isabella S. Gallardo, Cyrus J. Ghorbani, Kyle M. Hinaga, Analynn T. Nguyen, Edward H. T. Pham, Shaun M. K. McKinnie
This study investigates the substrate specificity and functional residues of the nonheme iron(II) α-ketoglutarate-dependent hydroxylase BesE using chemical synthesis and enzymology.
Journal of Natural Products · Dec 30, 2025Peer-reviewedBiochemistry