Shaun M. K. McKinnie

This paper integrates MALDI-MS/MS into a bioinformatics platform to enable rapid metabolite annotation and strain prioritization from microbial colonies.

IDBac provides a centralized database and platform for bacterial identification via MALDI-TOF MS, enabling spectral comparison and analysis of bacterial isolates.

The paper develops a MALDI-TIMS-MS platform for high-throughput screening of isomeric product ratios from enzyme libraries, identifying variants with improved KAL conversion.

This study identifies enzymes involved in amino acid incorporation into the antibiotic TLN-05220 using metabolomic and genomic analyses.

This study investigates the substrate specificity and functional residues of the nonheme iron(II) α-ketoglutarate-dependent hydroxylase BesE using chemical synthesis and enzymology.

This study solves the structure of a selective bromoperoxidase and identifies mechanisms for site-selective halogenation through distinct pockets and a camera shutter mechanism.

The paper identifies a subfamily of vanadium-dependent haloperoxidases that brominate alkyl quinolone quorum sensing signals, revealing their role in microbial chemical ecology.