Structural basis for the transport and regulation mechanism of the Multidrug resistance-associated protein 2
Eriko Koide, Harlan Linver Pietz, Beltran JB, Jue Chen
This study determines the cryo-EM structures of MRP2 in three conformational states, revealing its transport mechanism and substrate recognition.
Nature Communications · Jan 8, 2025Peer-reviewedBiophysics