Shift in pre-existing antibiotic heteroresistance explains AST change from susceptible to resistant during patient treatment
Ben Kittleson, Carter N. Abbott, Keith S. Kaye, David S. Weiss
The paper shows that a shift in pre-existing antibiotic heteroresistance, not de novo mutation, explains a change from susceptible to resistant classification during treatment.
bioRxiv · Nov 27, 2025 · PreprintMicrobiology