Author

Benjamin C. Lehne

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:fine-mapping· 1 Assay:GWAS summary statistics· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Alain Gerald BertoniiD· 1 shared Albert V. SmithiD· 1 shared Allan R LinnebergiD· 1 shared Andrew D. Jenkinson· 1 shared Anne E. JusticeiD· 1 shared Anne Tybjærg‐Hansen· 1 shared Annemari KäräjämäkiiD· 1 shared Anubha MahajaniD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Alain Gerald BertoniORCID

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2 papers

Recent·Most cited

Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes

Liam McAllan, Damir Baranas̆ić, Sergio Villicaña, Scarlett Brown, Weihua Zhang, Benjamin C. Lehne, Marco Adamo, Andrew D. Jenkinson, Mohamed Elkalaawy, Borzoueh Mohammadi, Masoomeh Hashemi, Nadia J. Fernandes, Nathalie Lambie, Richard Williams, Colette Christiansen, , William R. Scott

This study identifies DNA methylation changes associated with extreme obesity and finds causal effects on obesity and metabolic disturbances using Mendelian Randomisation.

Nature Communications · May 15, 2023Peer-reviewedGenetic & Genomic Medicine

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

Anubha Mahajan, Jennifer Wessel, Sara M. Willems, Wei Zhao, Neil R. Robertson, Audrey Y. Chu, Wei Gan, Hidetoshi Kitajima, Daniel Taliun, Nigel William Rayner, Xiuqing Guo, Yingchang Lu, Man Li, Richard A. Jensen, Yao Hu, , Jun Liu

This study identifies 16 causal coding variants in type 2 diabetes using fine-mapping and shows that one third of signals are false leads.

Nature Genetics · Apr 1, 2018Peer-reviewedGenetics