Author

Richard A. Jensen

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetics· 3 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:fine-mapping· 3 Assay:GWAS summary statistics· 3 Assay:whole-exome sequencing· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Jennifer A. BrodyiD· 4 shared Lawrence F. BielakiD· 4 shared Audrey Y. ChuiD· 3 shared Ayşe DemirkaniD· 3 shared Hidetoshi KitajimaiD· 3 shared Hugoline G. de HaaniD· 3 shared Ivan BrandslundiD· 3 shared Jie YaoiD· 3 shared

Activity by Year

2018-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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4 shared papersGenetics

Jennifer A. BrodyORCID

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4 papers

Recent·Most cited

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Anubha Mahajan, Cassandra Nichole Spracklen, Weihua Zhang, Maggie C.Y. Ng, Lauren E. Petty, Hidetoshi Kitajima, Grace Z. Yu, Sina Rüeger, Leo Speidel, Young Jin Kim, Momoko Horikoshi, Josep Maria Mercader, Daniel Taliun, Sanghoon Moon, Soo‐Heon Kwak, , Mary Cushman

This study identifies 277 T2D loci using diverse populations and improves fine-mapping to assess causal genes and mechanisms, enhancing clinical translation.

Discovery Research Portal (University of Dundee) · Jan 1, 2022Peer-reviewedGenetic & Genomic Medicine

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

Ji Chen, Cassandra Nichole Spracklen, Gaëlle Marenne, Arushi Varshney, Laura J. Corbin, Jian’an Luan, Sara M. Willems, Ying Wu, Xiaoshuai Zhang, Momoko Horikoshi, Thibaud Boutin, Reedik Mägi, Johannes Waage, Achilleas Pitsillides, Ruifang Li‐Gao, , Michael H Preuss

This study identifies 242 genetic loci for glycaemic traits using trans-ancestry meta-analysis, finding 99 novel loci and improved fine-mapping resolution compared to single-ancestry analyses.

bioRxiv · Jul 23, 2020 · PreprintGenetics

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

Natasha Hui Jin Ng, Sara M. Willems, Juan Fernandez, Rebecca S. Fine, Eleanor Wheeler, Jennifer Wessel, Hidetoshi Kitajima, Gaëlle Marenne, Jana K. Rundle, Xueling Sim, Hanieh Yeghootkar, Nicola L. Beer, Anne Raimondo, Andrei I. Tarasov, Soren K. Thomsen, , Abbas Dehghan

The paper identifies genetic variants and transcripts associated with glycemic traits by analyzing exome-array data from 144,600 individuals, highlighting tissue-specific roles in glucose regulation.

bioRxiv · Oct 3, 2019 · PreprintGenetics

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

Anubha Mahajan, Jennifer Wessel, Sara M. Willems, Wei Zhao, Neil R. Robertson, Audrey Y. Chu, Wei Gan, Hidetoshi Kitajima, Daniel Taliun, Nigel William Rayner, Xiuqing Guo, Yingchang Lu, Man Li, Richard A. Jensen, Yao Hu, , Jun Liu

This study identifies 16 causal coding variants in type 2 diabetes using fine-mapping and shows that one third of signals are false leads.

Nature Genetics · Apr 1, 2018Peer-reviewedGenetics