Deciphering the Evolutionary History of Complex Rearrangements in Head and Neck Cancer Patients Using Multi-Omic Approach
Jeesoo Chae, Jin Seok Lee, Jongkeun Park, Dong-Sung Lee, Weon Seo Park, Benjamin Clock, Jesse R. Dixon, Yuh‐Seog Jung, Dongwan Hong
This study uses a multi-omic approach to analyze complex genomic rearrangements in head and neck cancers, identifying HPV-mediated instability and enhancer hijacking as drivers of oncogene overexpression.
bioRxiv · Aug 19, 2022 · PreprintGenomics