GenomicsbioRxivPreprint
Deciphering the Evolutionary History of Complex Rearrangements in Head and Neck Cancer Patients Using Multi-Omic Approach
Jeesoo Chae, Jin Seok Lee, Jongkeun Park…·Dongwan Hong
This study uses a multi-omic approach to analyze complex genomic rearrangements in head and neck cancers, identifying HPV-mediated instability and enhancer hijacking as drivers of oncogene overexpression.
DOI 10.1101/2022.08.19.504509