Author

Benjamin J. Hu

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexander J. SodtiD· 1 shared Eric RosenbergiD· 1 shared Frank HeinrichiD· 1 shared Jess LiiD· 1 shared Margaret E. JohnsoniD· 1 shared Olivier SoubiasiD· 1 shared Paul A. RandazzoiD· 1 shared R. Andrew ByrdiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alexander J. SodtORCID

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1 paper

Recent·Most cited

The PH domain in the ArfGAP ASAP1 drives catalytic activation through an unprecedented allosteric mechanism

Olivier Soubias, Samuel L. Foley, Xiaoying Jian, Rebekah A. Jackson, Yue Zhang, Eric Rosenberg, Benjamin J. Hu, Jess Li, Frank Heinrich, Margaret E. Johnson, Alexander J. Sodt, Paul A. Randazzo, R. Andrew Byrd

The study reveals an allosteric mechanism by which the PH domain of ASAP1 enhances Arf1 GTPase activity through structural and dynamic interactions on a membrane surface.

Nature Communications · Sep 30, 2025Peer-reviewedBiochemistry