Author

Benjamin R. Yerxa

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Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Ashwath Jayagopal· 1 shared Christopher H. Tipper· 1 shared Devin S. McDougaldiD· 1 shared George Magrath· 1 shared Jason LeeiD· 1 shared Mayur ChoudharyiD· 1 shared Sachini U. Siriwardena· 1 shared Sally Tucker· 1 shared

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2026-2026 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperGenetics

Ashwath Jayagopal

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1 paper

Recent·Most cited

Functional Validation of Known BEST1 Variants Using a Robust Halide-Sensitive YFP Quenching Assay

Sachini U. Siriwardena, Mayur Choudhary, Jason Lee, Benjamin R. Yerxa, Sally Tucker, George Magrath, Devin S. McDougald, Christopher H. Tipper, Ashwath Jayagopal

The paper develops a halide-sensitive YFP quenching assay to functionally validate BEST1 variants and distinguish loss-of-function from gain-of-function mutations.

bioRxiv · Oct 24, 2026 · PreprintGenetics