Shared effect modeling reveals that a fraction of autoimmune disease associations are consistent with eQTLs in three immune cell types
Sung Chun, Alexandra Casparino, Nikolaos Patsopoulos, Damien Croteau-Chonka, Benjamin Raby, Philip De Jager, Shamil Sunyaev, Chris Cotsapas
This study identifies that about 25% of autoimmune disease loci have eQTLs driven by the same genetic effect using a shared effect modeling approach.
bioRxiv · May 12, 2016Genetics