Author

Nikolaos Patsopoulos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:GWAS / association mapping· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Alexander GuseviD· 1 shared Alexandra Casparino· 1 shared Benjamin Neale· 1 shared Benjamin Raby· 1 shared Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study the Discovery· 1 shared Bjarni Vilhjalmsson· 1 shared Bogdan Pasaniuc· 1 shared Carlos Pato· 1 shared

Activity by Year

2015-2016 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alexander GusevORCID

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2 papers

Recent·Most cited

Shared effect modeling reveals that a fraction of autoimmune disease associations are consistent with eQTLs in three immune cell types

Sung Chun, Alexandra Casparino, Nikolaos Patsopoulos, Damien Croteau-Chonka, Benjamin Raby, Philip De Jager, Shamil Sunyaev, Chris Cotsapas

This study identifies that about 25% of autoimmune disease loci have eQTLs driven by the same genetic effect using a shared effect modeling approach.

bioRxiv · May 12, 2016Genetics

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni Vilhjalmsson, Jian Yang, Hilary Kiyo Finucane, Alexander Gusev, Sara Lindstrom, Stephan Ripke, Giulio Genovese, Po-Ru Loh, Gaurav Bhatia, Ron Do, Tristian Hayeck, Hong-Hee Won, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study the Discovery, Sekar Kathiresan, , Nick J Patte

This paper introduces LDpred, a method that improves polygenic risk score accuracy by modeling linkage disequilibrium, showing increased R2 values in schizophrenia and multiple sclerosis datasets.

The American Journal of Human Genetics · Oct 1, 2015Peer-reviewedBioinformatics