Epigenetic reprogramming by 5-aza-dC alters gene methylation and suppresses aggression in founding queens of the California harvester ant Pogonomyrmex californicus.
Tania Chavarria Pizarro, Mohammed Errbii, Benne Köster, Mjtia Möhleke, Lukas Schrader, Juergen Gadau
This study shows that DNA demethylation with 5-aza-dC reduces aggression in founding queens of P. californicus, suggesting an epigenetic role in social behavior.
bioRxiv · Sep 11, 2025 · PreprintAnimal Behavior & Cognition