Massive transient damage of the olfactory epithelium associated with infection of sustentacular cells by SARS-CoV-2 in golden Syrian hamsters
Bertrand Bryche, Audrey Saint-Albin Deliot, Séverine Murri, Sandra Lacôte, Coralie Pulido, Meriadeg Ar Gouilh, Sandrine Lesellier, Alexandre Servat, Marine Wasniewski, Evelyne Picard Meyer, Élodie Monchâtre-Leroy, Romain Volmer, Olivier Rampin, Ronan Le Goffic, Philippe Marianneau, Nicolas Meunier
This study shows SARS-CoV-2 infection causes rapid and severe damage to the olfactory epithelium in golden Syrian hamsters, primarily through infection of sustentacular cells and immune cell infiltration, leading to anosmia.
bioRxiv · Jun 16, 2020Neuroscience