NELFA-mediated promoter-proximal pausing restrains YAP-driven transcription and shapes context-dependent outcomes in breast cancer
Bhavesh Vasave, Aadya Atreya, Rishabh Kulkarni, Sanket Nagarkar, Khushi Salvi, Chaitanyanand B. Koppiker, L S Shashidhara, Madhura Kulkarni
This study shows NELFA suppresses YAP-driven transcription in breast cancer, with context-dependent effects on survival outcomes.
bioRxiv · Dec 29, 2025 · PreprintCancer Biology