Cell Fate Clusters in ICM Organoids Arise from Cell Fate Heredity & Division - a Modeling Approach
Tim Liebisch, Armin Drusko, Biena Mathew, Ernst H. K. Stelzer, Sabine Fischer, Franziska Matthäus
The paper develops an agent-based model to quantify how cell proliferation and fate heredity contribute to cell lineage clustering in ICM organoids, showing that clustering arises from division rather than random fate assignment.
Scientific Reports · Dec 29, 2020Peer-reviewedSystems Biology