Ernst H. K. Stelzer

This study shows that Smac mimetics induce apoptosis in breast cancer organoids and that necroptosis, associated with inflammation, can be inhibited by LUBAC inhibitors.

This paper introduces a hybrid bioprinting-electrospinning platform for customizable wound healing dressings using nanofibers and mesenchymal cell spheroids, showing improved cell viability and wound closure.

The paper introduces an image analysis pipeline to segment, quantify, and visualize contraction waves in 2D+t and 3D+t microscopy data of Tribolium castaneum embryos, revealing novel dynamics in extra-embryonic membranes.

This paper introduces open-hardware solutions for light sheet microscopy specimen chambers using 3D printing, silicone injection moulding, and FEP-foil thermoforming to improve flexibility, sealing, and contamination prevention.

This study investigates how mTOR signaling, through mTORC1 and mTORC2, influences the growth and internal architecture of human breast cancer spheroids.

The paper identifies enhancers in Tribolium that regulate wavelike gene expression patterns by distinguishing dynamic and static enhancers.

The paper develops an agent-based model to quantify how cell proliferation and fate heredity contribute to cell lineage clustering in ICM organoids, showing that clustering arises from division rather than random fate assignment.

The paper identifies foxQ2 as a key regulator of midline brain structures in Tribolium castaneum, showing its role in the development of the central complex and linking it to an ancestral neuroendocrine center.

The paper investigates how three-dimensional cell neighbourhoods in mouse blastocysts influence cell fate decisions by analyzing NANOG and GATA6 expression patterns.