Franziska Matthäus

The paper introduces an image analysis pipeline to segment, quantify, and visualize contraction waves in 2D+t and 3D+t microscopy data of Tribolium castaneum embryos, revealing novel dynamics in extra-embryonic membranes.

The paper develops an agent-based model to quantify how cell proliferation and fate heredity contribute to cell lineage clustering in ICM organoids, showing that clustering arises from division rather than random fate assignment.