KYLO-0603, a novel liver-targeting, thyroid hormone recep-tor-β agonist for the treatment of MASH
Xueqin Lu, Shengjun Wang, Yanchun Du, Bixian Xie, Qingyan Chen, Jinzhen Lin, Bailing Chen, Kunyuan Cui
Kylo-0603, a THR-β agonist, reduces MASH markers and fibrosis in mice, showing potential as a therapeutic for MASH.
bioRxiv · Feb 9, 2025 · PreprintBiochemistry