In vitro activity of combination formulations of the novel metallo-β-lactamase (MBL) inhibitor APC148 with comparator treatments against 176 MBL-containing Enterobacterales isolates from the SENTRY Antimicrobial Surveillance Program (2019-2022)
Veronika Smith, Bjorn Klem, B. Bolstad, Hanne Cecilie Winther-Larsen, Ole Andreas Økstad, Pål Rongved
This study evaluates the in vitro activity of APC148 combined with carbapenems against MBL-producing Enterobacterales isolates, showing high susceptibility rates.
bioRxiv · Mar 15, 2026 · PreprintMicrobiology