System-level characterization of engineered and evolved formatotrophic E. coli strains
Suzan Yilmaz, Boas Kanis, Rensco A. H. Hogers, Sara Benito-Vaquerizo, Jörg Kahnt, Timo Glatter, Beau B. Dronsella, Tobias J. Erb, Maria Suarez Diez, Nico J. Claassens
This study investigates why engineered E. coli strains for formate utilization do not reach theoretical biomass yields and identifies metabolic bottlenecks and evolutionary changes to improve them.
Synthetic and Systems Biotechnology · Mar 5, 2025Peer-reviewedSynthetic Biology