Timo Glatter

This study identifies 338 previously unannotated small open reading frames in UPEC strain CFT073, with functional evidence for nine intergenic sORFs and potential roles in stress response.

The paper shows how two small proteins, SafA and MgrB, work together with magnesium to control the PhoQ/PhoP signaling system in E. coli, enhancing sensitivity to environmental changes.

This paper presents the first cryo-EM structure of DAB2, revealing a PMF-driven CO2 hydration mechanism in chemolithoautotrophs.

This paper combines adaptive laboratory evolution and machine learning to engineer a methylsuccinate module for synthetic C1 metabolism in E. coli, achieving growth in three weeks versus six months with evolution alone.

The paper shows that glycoproteins co-purify with RNA during glycoRNA isolation, suggesting they contribute glycans to glycoRNA preparations.

This study establishes the formyl phosphate route for formate assimilation in E. coli through adaptive evolution and rational engineering, enabling formate-dependent growth.

This study identifies PhaR as a key regulator of PHB-mediated metabolic adaptation in S. meliloti, revealing its impact on carbon metabolism and exopolysaccharide production.

This paper shows that phosphorylated EpsW activates exopolysaccharide biosynthesis by promoting EpsZ dimerization in Myxococcus xanthus.

This study shows Yersinia enterocolitica suppresses T3SS expression and adhesion at high cell densities through VirF downregulation and CsrBC-mediated mechanisms.

This study identifies NAD-dependent dehydrogenases in Paracoccus denitrificans that enable efficient bacterial growth on ethylene glycol, with implications for biotechnological applications.

This study identifies the HflK-HflC complex as essential for aerobic respiration in E. coli by regulating IspG abundance and ubiquinone levels.

This study identifies EcpK as a bacterial tyrosine pseudokinase essential for exopolysaccharide biosynthesis in Myxococcus xanthus, showing it functions as a scaffold rather than through phosphorylation.

This study investigates why engineered E. coli strains for formate utilization do not reach theoretical biomass yields and identifies metabolic bottlenecks and evolutionary changes to improve them.

This paper identifies DdiA as a transcriptional regulator in Myxococcus xanthus that controls a LexA-independent DNA damage response, balancing mutagenesis and fitness.

This paper presents a cell-free system for producing small membrane proteins in vitro, demonstrating their functional activity and utility for downstream studies.

This paper presents a computational workflow for designing and testing E. coli metabolic sensors that detect glyoxylate and glycolate across a wide concentration range, with applications in bioengineering and environmental monitoring.

This study evolves an engineered microbial community to show how metabolic interactions increase, leading to interdependence and indirect selection for mutualism.

This study identifies multiple transcriptional regulators controlling glycolate metabolism in Paracoccus denitrificans, revealing a complex regulatory network for carbon assimilation.

This study establishes Chlamydomonas reinhardtii as a platform for chloroplast synthetic biology, enabling high-throughput engineering of plastomes and demonstrating improved biomass production through synthetic pathways.

This study shows that simulated microgravity increases the production of infectious bacteriophage T7 virions in cell-free reactions.

The paper shows that Dbp2 is essential for proper 3'-end processing of mRNA by interacting with CPAC and regulating its availability for polyadenylation.

This study constructs a metabolic and genetic linked in vitro network that generates its own building blocks from non-living matter and demonstrates life-like behavior.

This study replaces the glycerate pathway with the β-hydroxyaspartate cycle in Pseudomonas putida, resulting in faster growth and higher biomass yield on ethylene glycol.

The paper engineers a synthetic one-carbon fixation pathway in Cupriavidus necator that achieves higher biomass yield than the native Calvin Cycle.