Nociceptive stimuli activate the hypothalamus-habenula circuit to inhibit the mesolimbic reward system
Soo Min Lee, Yu Fan, Bonghyo Lee, Sang Chan Kim, Kyle B. Bills, Scott C. Steffensen, Hee Young Kim
This study shows that nociceptive stimuli activate the hypothalamus-habenula circuit, which inhibits the mesolimbic reward system and reduces cocaine-seeking behavior.
bioRxiv · Nov 25, 2021 · PreprintNeuroscience