Fig4 confers tolerance to rapamycin in a Ste20-dependent manner independent of the Vac14 scaffold
Hannah E. Reeves, Anna King, Imran Khan, Asha Thomas, Corey Chung, Lauren Dotson, Anirudan Sivaprakash, Harrison A. Hall, Alim Habib, Sophia Rosella Lee, Bonnie Lloyd, Caroline L. Darbro, Bethany S. Strunk
The paper shows that Fig4 mutants in yeast confer rapamycin tolerance independently of Vac14 through Ste20-dependent mechanisms, suggesting Fig4 functions outside the Fab1-Vac14-Fig4 complex.
bioRxiv · Jul 12, 2024 · PreprintCell Biology