A Bio-inspired Latent TGF-β Conjugated Scaffold Improves Neocartilage Development
Tianbai Wang, Celina C. Maldonado, Bor-Lin Huang, Budbazar Enkhjargal, Andrew Martin, Matthew D. Layne, Joanne E. Murphy-Ullrich, Mark W. Grinstaff, Michael B. Albro
This paper develops LTGF-β conjugated scaffolds to improve neocartilage development by mimicking native TGF-β activation, achieving better mechanical and biochemical properties compared to conventional TGF-β supplementation.
bioRxiv · Feb 3, 2025 · PreprintBioengineering