The impact of tumor stromal architecture on therapy response and clinical progression
Philipp M. Altrock, Nara Yoon, Joshua A. Bull, Hao Wu, Javier Ruiz-Ramírez, Daria Miroshnychenko, Gregory J. Kimmel, Eunjung Kim, Robert J. Vander Velde, Katarzyna Rejniak, Brandon J. Manley, Fabian Spill, Andriy Marusyk
This paper investigates how tumor stromal architecture influences therapy response and resistance in lung, breast, and kidney cancers using mathematical models, experimental studies, and clinical analysis.
bioRxiv · Oct 24, 2018 · PreprintCancer Biology