Author

Brendan D. Zapp

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

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Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:software / tool· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alan F. RubiniD· 1 shared Alexis T. ChangiD· 1 shared Douglas M. FowleriD· 1 shared Jill M. JohnseniD· 1 shared John P. SheehaniD· 1 shared Kathryn M. SheldoniD· 1 shared Kerry W LannertiD· 1 shared Kristen J. Holmes· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Alan F. RubinORCID

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1 paper

Recent·Most cited

Multiplex, multimodal mapping of variant effects in secreted proteins

Nicholas A. Popp, Rachel L. Powell, Melinda K. Wheelock, Kristen J. Holmes, Brendan D. Zapp, Kathryn M. Sheldon, Shelley Nakaya Fletcher, Xiaoping Wu, Shawn Fayer, Alan F. Rubin, Kerry W Lannert, Alexis T. Chang, John P. Sheehan, Jill M. Johnsen, Douglas M. Fowler

The paper introduces MultiSTEP, a method to assess variant effects in secreted proteins, and applies it to coagulation factor IX, identifying functional variants and reclassifying uncertain ones.

bioRxiv · Apr 1, 2024 · PreprintGenomics