Author
University of WashingtonORCID 0000-0001-9374-3070Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Nick Moore, Callum J. Sargeant, Matthew John Wakefield…·Alan F. Rubin
CountESS provides a flexible, graphical pipeline for DMS analysis, supporting diverse workflows and input formats to generate variant scores.
Nicholas A. Popp, Rachel L. Powell, Melinda K. Wheelock…·Douglas M. Fowler
The paper introduces MultiSTEP, a method to assess variant effects in secreted proteins, and applies it to coagulation factor IX, identifying functional variants and reclassifying uncertain ones.
John C. Rose, Nicholas A. Popp, Chris D. Richardson…·Douglas M. Fowler
This paper introduces dead-RNAs (dRNAs) to suppress unwanted CRISPR/Cas9 off-target and HDR-corrected site cleavage, enabling precise genome editing.