Intravenous BCG induces a more potent airway and lung immune response than intradermal BCG in SIV-infected macaques
Solomon Jauro, Erica C. Larson, Janelle L. Gleim, Brendon Wahlberg, M. A. Rodgers, Julia C. Chehab, Alondra E. Lopez-Velazques, Cassaundra L. Ameel, Jaime A. Tomko, Jennifer Sakal, Todd DeMarco, Henry Jacob Borish, Pauline A Maiello, Elizabeth Lake Potter, Mario Roederer, , Charles A. Scanga
This study compares intravenous and intradermal BCG vaccination in SIV-infected macaques, finding IV BCG induces stronger airway and lung immune responses, including TRM cells and polyfunctional T cells.
The Journal of Immunology · Sep 23, 2024Peer-reviewedImmunology