Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A
Brian D Grossman, Jack D. Sanford, Yuyi Zhu, Cynthia B. Zeller, John E. Weldon
This study investigates how furin trafficking affects the efficacy of PE-based immunotoxins and suggests furin as a target to enhance their effectiveness.
Biology Open · Jun 9, 2025Peer-reviewedCell Biology