Assessing substrate scope of the cyclodehydratase LynD by mRNA display-enabled machine learning models
Emma G. Steude, Henry Dieckhaus, Jarrett M. Pelton, J. Ren, Brian Kuhlman, Albert A. Bowers
This paper uses mRNA display and machine learning to predict substrate promiscuity of the RiPP cyclodehydratase LynD and identify epistatic interactions.
Biochemistry · Jun 10, 2025Peer-reviewedBiochemistry