Author

Brian Ritchey

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jonathan D. SmithiD· 2 shared Alexander M. Alzayed· 1 shared C. Alicia TraughberiD· 1 shared Eve Schodowski· 1 shared John BarnardiD· 1 shared Juying HaniD· 1 shared Peggy Robinet· 1 shared Qimin HaiiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Jonathan D. SmithORCID

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2 papers

Recent·Most cited

Genetic Variant in 3' Untranslated Region of the Mouse Pycard Gene Regulates Inflammasome Activity

Brian Ritchey, Qimin Hai, Juying Han, John Barnard, Jonathan D. Smith

The paper identifies a SNP in the 3' UTR of the Pycard gene in mice that affects mRNA stability and inflammasome activity through CRISPR/Cas9 editing.

eLife · Jul 1, 2021Peer-reviewedGenetics

QTL analysis of macrophages from an AKR/JxDBA/2J intercross identified the Gpnmb gene as a modifier of lysosome function

Peggy Robinet, Brian Ritchey, Shuhui Wang Lorkowski, Alexander M. Alzayed, Sophia DeGeorgia, Eve Schodowski, C. Alicia Traughber, Jonathan D. Smith

This study identifies Gpnmb as a modifier of lysosome function in macrophages using QTL analysis in an AKR/JxDBA/2J intercross, showing its impact on proteolysis but not cholesterol metabolism.

Scientific Reports · May 13, 2021Peer-reviewedGenetics