Engineered phages evade the complete defense repertoire of highly phage-resistant MRSA clinical isolates
Sarah M. Voss, Katharine C. King, Devin J. Hunt, Adam A. Wilson, Bruria Samuel, Orazio Bagno, Peter F.W. Sparklin, Bridget Cassata, Joshua W. Modell
The paper demonstrates engineered phages can evade multiple defense systems in MRSA strains, preventing resistance emergence and offering a strategy for next-generation phage therapy.
bioRxiv · Mar 26, 2026 · PreprintMicrobiology