Effects of a Cancer-Associated Mutation and Multiple SerinePhosphorylation on Poly(ADP-Ribose) Polymerase 2
Bridget Todd Hughes, Shubham Chatterjee, Mozhdeh Ghafari, Gerardo Andrés Cisneros
This paper investigates how a cancer-associated mutation and serine phosphorylation affect the structure and function of PARP2, showing that PTMs can mitigate the mutation's structural impact.
Biophysical Journal · Jul 28, 2025Peer-reviewedBiophysics