Author

Shubham Chatterjee

The University of Texas at DallasORCID 0000-0002-5185-8459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Gerardo Andrés CisnerosiD· 2 shared Bridget Todd Hughes· 1 shared Mozhdeh GhafariiD· 1 shared Neel Shanmugam· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersBiophysics

Gerardo Andrés CisnerosORCID

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2 papers

Recent·Most cited

Effects of a Cancer-Associated Mutation and Multiple SerinePhosphorylation on Poly(ADP-Ribose) Polymerase 2

Bridget Todd Hughes, Shubham Chatterjee, Mozhdeh Ghafari, Gerardo Andrés Cisneros

This paper investigates how a cancer-associated mutation and serine phosphorylation affect the structure and function of PARP2, showing that PTMs can mitigate the mutation's structural impact.

Biophysical Journal · Jul 28, 2025Peer-reviewedBiophysics

Impact of a Cancer-Associated Mutation on Poly(ADP-ribose) Polymerase1 Inhibition

Neel Shanmugam, Shubham Chatterjee, Gerardo Andrés Cisneros

This study examines how the V762A PARP1 mutation affects binding of three PARP inhibitors, finding that talazoparib binds more effectively to the mutant and alters its dynamics differently than the wild-type.

The Journal of Physical Chemistry B · Feb 18, 2025Peer-reviewedBiophysics