Author

Brooke Emison

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 1

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Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew MugleriD· 1 shared Christopher W. LynniD· 1 shared Fabrisia AmbrosioiD· 1 shared Purushottam D. DixitiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperSystems Biology

Andrew MuglerORCID

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1 paper

Recent·Most cited

Decay in transcriptional information flow is a hallmark of cellular aging

Brooke Emison, Christopher W. Lynn, Andrew Mugler, Fabrisia Ambrosio, Purushottam D. Dixit

The paper quantifies age-related decline in transcriptional information flow using information theory and single-cell RNA-seq data, finding reduced mutual information between transcription factors and target genes.

bioRxiv · Oct 30, 2025 · PreprintSystems Biology