The QxxR Motif of RNA Helicase Me31B Is Essential for Drosophila Female Fertility and Germline Development
Raheem Mansoor, Anum Minhas, Abby Thomas, Ammara A Mansoor, Aidan McCambridge, Carol Dilts, John Eshak, Deep Govani, Brynn Nylin, Jonathan C. Trinidad, Ayah Y Kanaan, Evan Kara, Abraham Fielder, Isaac Fielder, Adriana Iglendza, , Ming Gao
This study investigates the role of the QxxR motif in Drosophila Me31B, showing that a mutation in this motif causes female sterility and germline defects without altering protein abundance or global transcriptome profiles.
bioRxiv · Aug 29, 2026 · PreprintGenetics