Transcriptome deregulation of peripheral monocytes in GBA-related Parkinson's disease
Giulietta Maria Riboldi, Ricardo A. Vialle, Elisa Navarro, Evan Udine, Kátia de Paiva Lopes, Jack Humphrey, Amanda Allan, Madison Parks, Brooklyn Henderson, Kelly Astudillo, Charalambos Argyrou, Maojuan Zhuang, Tamjeed Sikder, Josep Oriol Narcís, Shilpa Dilip Kumar, , Towfique Raj
The paper identifies transcriptomic changes in monocytes from GBA mutation carriers with Parkinson's disease, highlighting dysregulated pathways related to alpha-synuclein degradation and lysosomal function.
Molecular Neurodegeneration · Aug 17, 2022Peer-reviewedGenetic & Genomic Medicine