Author

Charalambos Argyrou

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Amanda AllaniD· 3 shared Elisa NavarroiD· 3 shared Evan UdineiD· 3 shared Giulietta Maria RiboldiiD· 3 shared Jack HumphreyiD· 3 shared Kátia de Paiva LopesiD· 3 shared Madison ParksiD· 3 shared Ricardo A. VialleiD· 3 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Amanda AllanORCID

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Author profile →

3 papers

Recent·Most cited

LRRK2 G2019S variant is associated with transcriptional changes in Parkinson's disease human myeloid cells under proinflammatory environment

Elisa Navarro, Anastasia G. Efthymiou, Daniele Mattei, Madison Parks, Giulietta Maria Riboldi, Ricardo A. Vialle, Evan Udine, Benjamin Z. Muller, Jack Humphrey, Amanda Allan, Charalambos Argyrou, Katia P Lopes, Alexandra Münch, Deborah Raymond, Rivka Sachdev, , Towfique Raj

This study shows the G2019S LRRK2 mutation alters transcriptomes of myeloid cells under proinflammatory conditions, affecting lipid metabolism and phagocytic function.

Journal of Neuroinflammation · Aug 8, 2026Peer-reviewedGenetics

Transcriptome deregulation of peripheral monocytes in GBA-related Parkinson's disease

Giulietta Maria Riboldi, Ricardo A. Vialle, Elisa Navarro, Evan Udine, Kátia de Paiva Lopes, Jack Humphrey, Amanda Allan, Madison Parks, Brooklyn Henderson, Kelly Astudillo, Charalambos Argyrou, Maojuan Zhuang, Tamjeed Sikder, Josep Oriol Narcís, Shilpa Dilip Kumar, , Towfique Raj

The paper identifies transcriptomic changes in monocytes from GBA mutation carriers with Parkinson's disease, highlighting dysregulated pathways related to alpha-synuclein degradation and lysosomal function.

Molecular Neurodegeneration · Aug 17, 2022Peer-reviewedGenetic & Genomic Medicine

Discordant transcriptional signatures of mitochondrial genes in Parkinson's disease human myeloid cells

Elisa Navarro, Evan Udine, Kátia de Paiva Lopes, Madison Parks, Giulietta Maria Riboldi, Brian M. Schilder, Jack Humphrey, Gijsje J. L. Snijders, Ricardo A. Vialle, Maojuan Zhuang, Tamjeed Sikder, Charalambos Argyrou, Amanda Allan, Michael J. Chao, Kurt W. Farrell, , Towfique Raj

The paper identifies discordant mitochondrial gene expression patterns in PD monocytes and microglia, revealing distinct transcriptomic alterations in these myeloid cell types.

Nature Aging · Sep 14, 2021Peer-reviewedNeuroscience