Borrelia burgdorferi BB0346 is an Essential, Structurally Variant LolA Homolog that is Primarily Required for Homeostatic Localization of Periplasmic Lipoproteins
Bryan T. Murphy, Jacob J. Wiepen, Danielle E. Graham, Selene K. Swanson, Maithri M. Kashipathy, Anne Cooper, K. P. Battaile, David K. Johnson, Laurence A. Florens, Jon S. Blevins, S. Lovell, Wolfram R. Zückert
This study identifies BB0346 as an essential LolA homolog in Borrelia burgdorferi that functions in a LolB-deficient lipoprotein sorting system, leading to mislocalization of inner membrane lipoproteins.
bioRxiv · Aug 6, 2024 · PreprintMicrobiology