3D Biomimetic Liver Cancer Model: Diethylnitrosamine-Induced Proteomic Dysregulations in Stromal-Epithelial Milieu
SALMMA SALAMAH SALIHAH, Bushra Bibi, Sehrish Khan, Muhammad Tahir, Sana Mahmood, Massoud Vosough, Agnese Razzoli, Simone Sidoli, Asma Gul
This study uses a 3D co-culture model to analyze proteomic changes in liver cancer induced by DEN, showing enhanced pathway enrichment and biomarker expression in 3D compared to 2D cultures.
bioRxiv · May 17, 2025 · PreprintCancer Biology