CXCR6 by increasing retention of memory CD8 T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer
R. Muthuswamy, A. R. McGray, S. Battaglia, W. He, A. Miliotto, C. A. Eppolito, B. D. Litchy, P. Shrikant, K. Odunsi, K. Odunsi
This study identifies CXCR6 as a marker for resident memory CD8 T cells in ovarian cancer, showing its role in enhancing tumor immunosurveillance through increased retention of these cells in the tumor microenvironment.
bioRxiv · Dec 2, 2020Immunology