Cancer BiologybioRxiv
CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells
S. Darvish Shafighi, S. M. Kiełbasa, J. Sepulveda-Yanez…·E. Szczurek
CACTUS integrates genomic and transcriptomic data to map single tumor cells to their clonal origins, improving accuracy in follicular lymphoma by combining exome, RNA-seq, and B-cell receptor sequencing.