Author

S. Darvish Shafighi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2 Assay:DNA methylation· 1

Frequent Co-Authors

E. Szczurek· 2 shared A. Carbone· 1 shared A. Geras· 1 shared A. Sahaf Naeini· 1 shared B. Jurzysta· 1 shared C. A. M. v. Bergen· 1 shared C. Engblom· 1 shared D. Cats· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

E. Szczurek

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 22, 2022

Tumoroscope: a probabilistic model for mapping cancer clones in tumor tissues

S. Darvish Shafighi, A. Geras, B. Jurzysta…·E. Szczurek

Tumoroscope maps cancer clones in tumor tissues by integrating spatial transcriptomics, whole exome sequencing, and pathological images to reveal spatial patterns and clone-specific gene expression.

DOI 10.1101/2022.09.22.508914

humanspatial transcriptomics

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Cancer BiologybioRxivJun 5, 2020

CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells

S. Darvish Shafighi, S. M. Kiełbasa, J. Sepulveda-Yanez…·E. Szczurek

CACTUS integrates genomic and transcriptomic data to map single tumor cells to their clonal origins, improving accuracy in follicular lymphoma by combining exome, RNA-seq, and B-cell receptor sequencing.

DOI 10.1186/s13073-021-00842-w

humanscRNA-seq

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