Efficacy of plasmid-encoded CRISPR-Cas antimicrobial is affected by competitive factors found in wild Enterococcus faecalis isolates
D. P. Araya, M. Islam, S. O. Moni, C. A. Ramjee, T.-V. C. Ngo, K. Palmer
This study evaluates the effectiveness of CRISPR-Cas antimicrobials against wild E. faecalis isolates and finds that competitive factors in these isolates reduce CRISPR-Cas efficacy.
bioRxiv · Mar 8, 2022 · PreprintMicrobiology