A VP2/3-derived peptide exhibits potent antiviral activity against BK and JC polyomaviruses by targeting a novel VP1 binding site
J. R. Kane, S. Fong, J. Shaul, A. Frommlet, A. O. Frank, M. Knapp, D. E. Bussiere, P. Kim, E. Ornelas, C. Cuellar, J. R. Abend, C. A. Wartchow
The paper identifies a VP2/3-derived peptide that inhibits BK and JC polyomaviruses by binding to a novel VP1 pore site, showing potent antiviral activity with low nanomolar affinity.
bioRxiv · Aug 8, 2019 · PreprintMicrobiology