COQ4 is required for the oxidative decarboxylation of the C1 carbon of Coenzyme Q in eukaryotic cells
L. Pelosi, L. Morbiato, A. Burgardt, F. Tonello, A. K. Bartlett, R. M. Guerra, K. K. Ferizhendi, M. A. Desbats, B. Rascalou, M. Marchi, L. Vazquez-Fonseca, C. Agosto, G. Zanotti, M. Roger-Margueritat, M. Alcazar-Fabra, , F. Pierrel
This study identifies COQ4 as catalyzing the oxidative decarboxylation of the C1 carbon in CoQ biosynthesis in eukaryotic cells.
bioRxiv · Nov 13, 2023Biochemistry