Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs.
C. B. Merrill, A. B. Montgomery, M. A. Pabon, A. R. Rodan, A. Rothenfluh
The paper uses ATAC-seq and RNA-seq to identify insulin-responsive enhancer regions in Drosophila cells and validates their inducibility with luciferase reporters.
bioRxiv · May 6, 2021Cell Biology